Cell-Free Fetal DNA in Plasma of Pregnant Women: Clinical Potential and Origin
نویسندگان
چکیده
منابع مشابه
cell free fetal dna testing in maternal blood of romanian pregnant women
background: the discovery of circulating fetal dna in maternal blood led to the discovery of new strategies to perform noninvasive testing for prenatal diagnosis. objective: the purpose of the study was to detect fetal aneuploidy at chromosomes 13, 18, 21, x, and y by analysis of fetal cell-free dna from maternal blood, without endangering pregnancy. materials and methods: this retrospective st...
متن کاملfetal sex determination using non-invasive method of cell-free fetal dna in maternal plasma of pregnant women during 6th– 10th weeks of gestation
in previous years, identification of fetal cells in maternal blood circulation has caused a new revolution in non-invasive method of prenatal diagnosis. low number of fetal cells in maternal blood and long-term survival after pregnancy limited the use of fetal cells in diagnostic and clinical applications. with the discovery of cell-free fetal dna (cffdna) in plasma of pregnant women, access to...
متن کاملCell free fetal DNA testing in maternal blood of Romanian pregnant women
BACKGROUND The discovery of circulating fetal DNA in maternal blood led to the discovery of new strategies to perform noninvasive testing for prenatal diagnosis. OBJECTIVE The purpose of the study was to detect fetal aneuploidy at chromosomes 13, 18, 21, X, and Y by analysis of fetal cell-free DNA from maternal blood, without endangering pregnancy. MATERIALS AND METHODS This retrospective s...
متن کاملNoninvasive fetal RHD genotyping using cell-free fetal DNA incorporating fetal RASSF1A marker in RhD-negative pregnant women in Korea
risk of HDFN, which can cause fetal anemia, hydrops, and intrauterine fetal death. Babies born with HDFN are at significant risk of neonatal morbidity and mortality [1,2]. Prenatal detection of the fetal RhD status in a pregnant woman with RhD-negative provides useful information for predicting the risk of HDFN and Noninvasive fetal RHD genotyping using cell-free fetal DNA incorporating fetal R...
متن کاملFetal RHD Genotyping Using Real-Time Polymerase Chain Reaction Analysis of Cell-Free Fetal DNA in Pregnancy of RhD Negative Women in South of Iran
Objective Maternal-fetal RhD antigen incompatibility causes approximately 50% of clinically significant alloimmunization cases. The routine use of prophylactic anti-D immunoglobulin has dramatically reduced hemolytic disease of the fetus and newborn. Recently, fetal RHD genotyping in RhD negative pregnant women has been suggested for appropriate use of anti-D immunoglobulin antenatal prophylaxi...
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ژورنال
عنوان ژورنال: Taiwanese Journal of Obstetrics and Gynecology
سال: 2005
ISSN: 1028-4559
DOI: 10.1016/s1028-4559(09)60122-4